10/22/2016 1:29 PM PDT BY TMZ STAFF
Shirley Manson went nuclear on a fan who dared to hurl a beer at her in the middle of a concert.
Shirley’s band, Garbage, was performing Friday night at Hollywood Forever in L.A., when the unruly fan tossed the can. The brewsky missed its apparent target, but Shirley responded in kind … opening up her own can of whoop-ass.
Manson fired up the fans with a battle cry that sounded very familiar.
Then again … Schlitz happens.